Neurocomputing (journal)

Neurocomputing is a peer-reviewed scientific journal covering research on artificial intelligence, machine learning, and neural computation. It was established in 1989 and is published by Elsevier. The editor-in-chief is Zidong Wang (Brunel University London). Independent scientometric studies noted that despite being one of the most productive journals in the field, it has kept its reputation across the years intact and plays an important role in leading the research in the area. The journal is abstracted and indexed in Scopus and Science Citation Index Expanded. According to the Journal Citation Reports, its 2023 impact factor is 5.5.

Apptek

Applications Technology (AppTek) is a U.S. company headquartered in McLean, Virginia that specializes in artificial intelligence and machine learning for human language technologies. The company provides both managed and professional services for natural language processing (NLP) technologies including automatic speech recognition (ASR), neural machine translation (MT), natural-language understanding (NLU) and neural speech synthesis. AppTek's Head of Science, Prof. Dr. -Ing Hermann Ney, was awarded the IEEE James L. Flanagan Speech and Audio Processing Award in 2019 and the ISCA Medal for Scientific Achievement in 2021 for his work in natural language processing. == History == AppTek was acquired in 1998 by Lernout & Hauspie (at the time a NASDAQ publicly traded company), AppTek organized a management buy-out and went private again in 2001. In 2014, the company sold its hybrid machine translation technology to eBay and has since rebuilt the platform to modern neural-based approaches for machine translation. In 2020, SOSi acquired non-controlling interest in AppTek and became an exclusive reseller of AppTek products for U.S. federal, state, and local government entities.

Rectified linear unit

In the context of artificial neural networks, the rectifier or ReLU (rectified linear unit) activation function is an activation function defined as the non-negative part of its argument, i.e., the ramp function: ReLU ⁡ ( x ) = x + = max ( 0 , x ) = x + | x | 2 = { x if x > 0 , 0 x ≤ 0 {\displaystyle \operatorname {ReLU} (x)=x^{+}=\max(0,x)={\frac {x+|x|}{2}}={\begin{cases}x&{\text{if }}x>0,\\0&x\leq 0\end{cases}}} where x {\displaystyle x} is the input to a neuron. This is analogous to half-wave rectification in electrical engineering. ReLU is one of the most popular activation functions for artificial neural networks, and finds application in computer vision and speech recognition using deep neural nets and computational neuroscience. == History == The ReLU was first used by Alston Householder in 1941 as a mathematical abstraction of biological neural networks. Kunihiko Fukushima in 1969 used ReLU in the context of visual feature extraction in hierarchical neural networks. In 1998, Gregory Woodbury demonstrated that the rectified linear function could account for a broad range of emergent properties in the visual cortex. His work showed that a single unified model could drive the joint development of refined retinotopic maps, ocular dominance columns, and orientation selectivity. By utilizing the rectifier's "cutoff" property, Woodbury achieved a close quantitative fit to biological data, matching the spatial periodicities and topographic refinement patterns observed in macaque and cat cortical maps. Furthermore, he extended this framework to adult plasticity, accurately replicating the spatial and temporal dynamics of lesion-induced cortical reorganization. This research established that the rectified linear response was a necessary mechanism for the stable self-organisation and maintenance of complex, multi-feature neural maps. In 2000, Hahnloser et al. argued that ReLU approximates the biological relationship between neural firing rates and input current, in addition to enabling recurrent neural network dynamics to stabilise under weaker criteria. Prior to 2010, most activation functions used were the logistic sigmoid (which is inspired by probability theory; see logistic regression) and its more numerically efficient counterpart, the hyperbolic tangent. Around 2010, the use of ReLU became common again. Jarrett et al. (2009) noted that rectification by either absolute or ReLU (which they called "positive part") was critical for object recognition in convolutional neural networks (CNNs), specifically because it allows average pooling without neighboring filter outputs cancelling each other out. They hypothesized that the use of sigmoid or tanh was responsible for poor performance in previous CNNs. Nair and Hinton (2010) made a theoretical argument that the softplus activation function should be used, in that the softplus function numerically approximates the sum of an exponential number of linear models that share parameters. They then proposed ReLU as a good approximation to it. Specifically, they began by considering a single binary neuron in a Boltzmann machine that takes x {\displaystyle x} as input, and produces 1 as output with probability σ ( x ) = 1 1 + e − x {\displaystyle \sigma (x)={\frac {1}{1+e^{-x}}}} . They then considered extending its range of output by making infinitely many copies of it X 1 , X 2 , X 3 , … {\displaystyle X_{1},X_{2},X_{3},\dots } , that all take the same input, offset by an amount 0.5 , 1.5 , 2.5 , … {\displaystyle 0.5,1.5,2.5,\dots } , then their outputs are added together as ∑ i = 1 ∞ X i {\displaystyle \sum _{i=1}^{\infty }X_{i}} . They then demonstrated that ∑ i = 1 ∞ X i {\displaystyle \sum _{i=1}^{\infty }X_{i}} is approximately equal to N ( log ⁡ ( 1 + e x ) , σ ( x ) ) {\displaystyle {\mathcal {N}}(\log(1+e^{x}),\sigma (x))} , which is also approximately equal to ReLU ⁡ ( N ( x , σ ( x ) ) ) {\displaystyle \operatorname {ReLU} ({\mathcal {N}}(x,\sigma (x)))} , where N {\displaystyle {\mathcal {N}}} stands for the gaussian distribution. They also argued for another reason for using ReLU: that it allows "intensity equivariance" in image recognition. That is, multiplying input image by a constant k {\displaystyle k} multiplies the output also. In contrast, this is false for other activation functions like sigmoid or tanh. They found that ReLU activation allowed good empirical performance in restricted Boltzmann machines. Glorot et al (2011) argued that ReLU has the following advantages over sigmoid or tanh: ReLU is more similar to biological neurons' responses in their main operating regime. ReLU avoids vanishing gradients. ReLU is cheaper to compute. ReLU creates sparse representation naturally, because many hidden units output exactly zero for a given input. They also found empirically that deep networks trained with ReLU can achieve strong performance without unsupervised pre-training, especially on large, purely supervised tasks. In 2017, the rectified linear function became a central component of the transformer architecture introduced in the Vaswani et al paper "Attention Is All You Need". Within every transformer layer, ReLU is utilized in the position-wise feed-forward networks (FFN), defined by Equation 2 of their paper: FFN ⁡ ( x ) = max ( 0 , x W 1 + b 1 ) W 2 + b 2 {\displaystyle \operatorname {FFN} (x)=\max(0,xW_{1}+b_{1})W_{2}+b_{2}} This equation is foundational to the model's capacity; while the attention mechanism determines the relationships between tokens, the ReLU-based FFN performs the majority of the numerical computation and houses the bulk of the model's parameters. The efficiency and scalability of this rectified framework triggered a global technological revolution, enabling the development of Large Language Models that have had a profound economic impact. The industrial response to this architecture—including the massive expansion of AI-specific hardware and the birth of the generative AI sector—has positioned the Transformer as a cornerstone of 21st-century infrastructure. During the post 2017 period of rapid AI advancement, the rectified linear unit function has been key to achieving increased model performance and scaling due to the fact that it zeros out responses that are immaterial for a given stimuli, preventing them from accumulating in massive scale models. It is the complete silencing of the parts of the model found to be stimuli-irrelevant during learning that allows for scaling. As the stimuli-irrelevant proportion of the model becomes more massive, these highly numerous connections within the model would inevitably accumulate during scaling no matter how small each individual response is. Therefore, the rectified linear unit function, with its absolute zeroing property, enabled the scaling to hundred billion parameter models and beyond. Early Transformer scaling giants like GPT-3 (2020) and Falcon-180B (2023) relied on the rectified linear unit function explicitly, while successors such as GPT-4 (2023) and Llama 3 (2024) utilized smoother variants like GELU or SwiGLU. These variants were used to improve training stability while fundamentally preserving the rectified principle of zeroing low responses. At the centre of modern artificial intelligence ReLU and its variants maintain absolute zero response across the bulk of the model at any one time, while maintaining approximately linear reponses for stimuli-relevant connections enabling high performance on each specific cognitive task. This feature of activation sparsity has been critical for massive scaling and performance gains of AI models right up to the present day. == Advantages == Advantages of ReLU include: Sparse activation: for example, in a randomly initialized network, only about 50% of hidden units are activated (i.e. have a non-zero output). Better gradient propagation: fewer vanishing gradient problems compared to sigmoidal activation functions that saturate in both directions. Efficiency: only requires comparison and addition. Scale-invariant (homogeneous, or "intensity equivariance"): max ( 0 , a x ) = a max ( 0 , x ) for a ≥ 0 {\displaystyle \max(0,ax)=a\max(0,x){\text{ for }}a\geq 0} . == Potential problems == Possible downsides can include: Non-differentiability at zero (however, it is differentiable anywhere else, and the value of the derivative at zero can be chosen to be 0 or 1 arbitrarily). Not zero-centered: ReLU outputs are always non-negative. This can make it harder for the network to learn during backpropagation, because gradient updates tend to push weights in one direction (positive or negative). Batch normalization can help address this. ReLU is unbounded. Redundancy of the parametrization: Because ReLU is scale-invariant, the network computes the exact same function by scaling the weights and biases in front of a ReLU activation by k {\displaystyle k} , and the weights after by 1 / k {\displaystyle 1/k} . Dying ReLU: ReLU neurons can sometimes be pushed into states

Rule-based machine learning

Rule-based machine learning (RBML) is a term in computer science intended to encompass any machine learning method that identifies, learns, or evolves 'rules' to store, manipulate or apply. The defining characteristic of a rule-based machine learner is the identification and utilization of a set of relational rules that collectively represent the knowledge captured by the system. Rule-based machine learning approaches include learning classifier systems, association rule learning, artificial immune systems, and any other method that relies on a set of rules, each covering contextual knowledge. While rule-based machine learning is conceptually a type of rule-based system, it is distinct from traditional rule-based systems, which are often hand-crafted, and other rule-based decision makers. This is because rule-based machine learning applies some form of learning algorithm such as Rough sets theory to identify and minimise the set of features and to automatically identify useful rules, rather than a human needing to apply prior domain knowledge to manually construct rules and curate a rule set. == Rules == Rules typically take the form of an '{IF:THEN} expression', (e.g. {IF 'condition' THEN 'result'}, or as a more specific example, {IF 'red' AND 'octagon' THEN 'stop-sign}). An individual rule is not in itself a model, since the rule is only applicable when its condition is satisfied. Therefore rule-based machine learning methods typically comprise a set of rules, or knowledge base, that collectively make up the prediction model usually known as decision algorithm. Rules can also be interpreted in various ways depending on the domain knowledge, data types(discrete or continuous) and in combinations. == RIPPER == Repeated incremental pruning to produce error reduction (RIPPER) is a propositional rule learner proposed by William W. Cohen as an optimized version of IREP.

Targeted maximum likelihood estimation

Targeted Maximum Likelihood Estimation (TMLE) (also more accurately referred to as Targeted Minimum Loss-Based Estimation) is a general statistical estimation framework for causal inference and semiparametric models. TMLE combines ideas from maximum likelihood estimation, semiparametric efficiency theory, and machine learning. It was introduced by Mark J. van der Laan and colleagues in the mid-2000s as a method that yields asymptotically efficient plug-in estimators while allowing the use of flexible, data-adaptive algorithms such as ensemble machine learning for nuisance parameter estimation. TMLE is used in epidemiology, biostatistics, and the social sciences to estimate causal effects in observational and experimental studies. Applications of TMLE include Longitudinal TMLE (LTMLE) for time-varying treatments and confounders. Variations in how the targeting step in TMLE is carried out have resulted in various versions of TMLE such as Collaborative TMLE (CTMLE) and Adaptive TMLE for improved finite-sample performance and automated variable selection. == History == The TMLE framework was first described by van der Laan and Rubin (2006) as a general approach for the construction of efficient plug-in estimators of smooth features of the data density. It was demonstrated in the context of causal inference and missing data problems. It was developed to address limitations of traditional doubly robust methods, such as Augmented Inverse Probability Weighting (AIPW), by respecting the plug-in principle in the sense that it respects that the target parameter is a function of the data density that is an element of the statistical model. TMLE estimates the data density or relevant parts of it with machine learning and targets these machine learning fits before it is plugged in the target parameter mapping. In this manner, a TMLE always respects global knowledge and satisfies known bounds such as that the target parameter is a probability . Since its introduction, TMLE has been developed in a series of theoretical and applied papers, culminating in book-length treatments of the method and its applications to survival analysis, adaptive designs, and longitudinal data. == Methodology == At its core, TMLE is a two-step estimation procedure: Initial estimation: Machine learning methods (such as the Super Learner ensemble) are used to obtain flexible estimates of nuisance parameters, such as outcome regressions and propensity scores. Targeting step: The initial estimate is updated by solving a score equation (the efficient influence function) so that the final estimator is consistent, asymptotically normal, and efficient under mild regularity conditions. The targeted machine learning fit is then mapped into the corresponding estimator of the target parameter by simply plugging it in the target parameter mapping. This approach balances the bias–variance trade-off by combining data-adaptive estimation with semiparametric efficiency theory. TMLE is doubly robust, meaning it remains consistent if either the outcome model or the treatment model is consistently estimated. === Formula === Here we explain the TMLE of the average treatment effect of a binary treatment on an outcome adjusting for baseline covariates. Consider i.i.d. observations O i = ( W i , A i , Y i ) {\displaystyle O_{i}=(W_{i},A_{i},Y_{i})} from a distribution P 0 {\displaystyle P_{0}} , where W {\displaystyle W} are baseline covariates, A {\displaystyle A} is a binary treatment, and Y {\displaystyle Y} is an outcome. Let Q ¯ ( a , w ) = E [ Y ∣ A = a , W = w ] {\displaystyle {\bar {Q}}(a,w)=\mathbb {E} [Y\mid A=a,W=w]} represent the outcome model and g ( a ∣ w ) = P ( A = a ∣ W = w ) {\displaystyle g(a\mid w)=P(A=a\mid W=w)} represent the propensity score. The average treatment effect (ATE) is given by ψ 0 = E { Q ¯ ( 1 , W ) − Q ¯ ( 0 , W ) } . {\displaystyle \psi _{0}=\mathbb {E} \{{\bar {Q}}(1,W)-{\bar {Q}}(0,W)\}.} A basic TMLE for the ATE proceeds as follows: Step 1: Estimate initial models. Obtain estimates Q ¯ ^ ( a , w ) {\displaystyle {\hat {\bar {Q}}}(a,w)} and g ^ ( a ∣ w ) {\displaystyle {\hat {g}}(a\mid w)} , often using flexible methods such as Super Learner. Step 2: Compute the clever covariate. Define: H ( A , W ) = A g ^ ( 1 ∣ W ) − 1 − A g ^ ( 0 ∣ W ) . {\displaystyle H(A,W)={\frac {A}{{\hat {g}}(1\mid W)}}-{\frac {1-A}{{\hat {g}}(0\mid W)}}.} Step 3: Estimate the fluctuation parameter. Fit a logistic regression of Y {\displaystyle Y} on H ( A , W ) {\displaystyle H(A,W)} with logit ⁡ ( Q ¯ ^ ( A , W ) ) {\displaystyle \operatorname {logit} ({\hat {\bar {Q}}}(A,W))} as offset. This yields ε ^ {\displaystyle {\hat {\varepsilon }}} , the MLE that solves the score equation: 1 n ∑ i = 1 n H ( A i , W i ) { Y i − Q ¯ ^ ε ( A i , W i ) } = 0. {\displaystyle {\frac {1}{n}}\sum _{i=1}^{n}H(A_{i},W_{i}){\big \{}Y_{i}-{\hat {\bar {Q}}}^{\varepsilon }(A_{i},W_{i}){\big \}}=0.} Step 4: Update the initial estimate. Apply the "blip" to obtain the targeted estimate: Q ¯ ^ ∗ ( A , W ) = expit ⁡ ( logit ⁡ ( Q ¯ ^ ( A , W ) ) + ε ^ H ( A , W ) ) . {\displaystyle {\hat {\bar {Q}}}^{}(A,W)=\operatorname {expit} {\Big (}\operatorname {logit} {\big (}{\hat {\bar {Q}}}(A,W){\big )}+{\hat {\varepsilon }}\,H(A,W){\Big )}.} Step 5: Compute the TMLE. The ATE estimate is: ψ ^ TMLE = 1 n ∑ i = 1 n [ Q ¯ ^ ∗ ( 1 , W i ) − Q ¯ ^ ∗ ( 0 , W i ) ] . {\displaystyle {\hat {\psi }}_{\text{TMLE}}={\frac {1}{n}}\sum _{i=1}^{n}{\big [}{\hat {\bar {Q}}}^{}(1,W_{i})-{\hat {\bar {Q}}}^{}(0,W_{i}){\big ]}.} Inference. The efficient influence function (EIF) for the ATE is: D ∗ ( O ) = H ( A , W ) { Y − Q ¯ ∗ ( A , W ) } + Q ¯ ∗ ( 1 , W ) − Q ¯ ∗ ( 0 , W ) − ψ . {\displaystyle D^{}(O)=H(A,W)\{Y-{\bar {Q}}^{}(A,W)\}+{\bar {Q}}^{}(1,W)-{\bar {Q}}^{}(0,W)-\psi .} The variance is estimated by σ ^ 2 = n − 1 ∑ i = 1 n ( D ∗ ( O i ) ) 2 {\displaystyle {\hat {\sigma }}^{2}=n^{-1}\sum _{i=1}^{n}{\big (}D^{}(O_{i}){\big )}^{2}} , yielding Wald-type confidence intervals ψ ^ TMLE ± z 1 − α / 2 σ ^ / n {\displaystyle {\hat {\psi }}_{\text{TMLE}}\pm z_{1-\alpha /2}\,{\hat {\sigma }}/{\sqrt {n}}} . Remark. For continuous outcomes, a linear fluctuation Q ¯ ^ ∗ = Q ¯ ^ + ε ^ H {\displaystyle {\hat {\bar {Q}}}^{}={\hat {\bar {Q}}}+{\hat {\varepsilon }}\,H} may be used instead. For bounded continuous outcomes, the logistic fluctuation (after rescaling Y {\displaystyle Y} to [ 0 , 1 ] {\displaystyle [0,1]} ) is often preferred for improved finite-sample performance. == Applications == TMLE has been applied in: Epidemiology: Estimating causal effects of exposures and interventions in observational cohort studies. Clinical trials and real-world evidence: The Targeted Learning roadmap provides a structured framework for generating and validating real-world evidence (RWE), bridging randomized trials and observational data using TMLE and related estimation techniques. This approach enables transparency, sensitivity analysis, and stronger causal inference for regulatory and clinical trial contexts. High-dimensional settings: Integration with ensemble methods for causal effect estimation. TMLE has been successfully applied in pharmacoepidemiology where a large number of covariates are automatically selected to adjust for confounding. In a study of post–myocardial infarction statin use and 1-year mortality, TMLE demonstrated robust performance relative to inverse probability weighting in scenarios with hundreds of potential confounders. == Derivatives and extensions == Longitudinal TMLE (LTMLE): A methodological extension of TMLE for longitudinal data with time-varying treatments, confounders, and censoring. It allows the estimation of dynamic treatment regimes and intervention-specific causal effects over time. This framework was originally introduced by van der Laan & Gruber (2012). Collaborative TMLE (CTMLE): Enhances finite-sample performance and variable selection by collaboratively fitting the treatment mechanism in conjunction with the target parameter. == Software == Several R packages implement TMLE and related methods: tmle: Functions for binary, categorical, and continuous outcomes. ltmle: Implementation for longitudinal data with time-varying treatments and outcomes. ctmle: Algorithms for collaborative TMLE and adaptive variable selection. SuperLearner: A theoretically grounded, cross-validated ensemble learning method that combines predictions from multiple algorithms to minimize predictive risk. Widely used in TMLE for estimating nuisance parameters. The original implementation is available as the R package SuperLearner. Recent machine learning platforms like H2O AutoML implement similar ensemble strategies, combining diverse learners in parallel and leveraging stacking and blending techniques, effectively functioning as a large-scale Super Learner.

Bright Computing

Bright Computing, Inc. was a developer of software for deploying and managing high-performance (HPC) clusters, Kubernetes clusters, and OpenStack private clouds in on-premises data centers as well as in the public cloud. In 2022, it was acquired by Nvidia. == History == Bright Computing was founded by Matthijs van Leeuwen in 2009, who spun the company out of ClusterVision, which he had co-founded with Alex Ninaber and Arijan Sauer. Alex and Matthijs had worked together at UK’s Compusys, which was one of the first companies to commercially build HPC clusters. They left Compusys in 2002 to start ClusterVision in the Netherlands, after determining there was a growing market for building and managing supercomputer clusters using off-the-shelf hardware components and open source software, tied together with their own customized scripts. ClusterVision also provided delivery and installation support services for HPC clusters at universities and government entities. In 2004, Martijn de Vries joined ClusterVision and began development of cluster management software. The software was made available to customers in 2008, under the name ClusterVisionOS v4. In 2009, Bright Computing was spun out of ClusterVision. ClusterVisionOS was renamed Bright Cluster Manager, and van Leeuwen was named Bright Computing’s CEO. In February 2016, Bright appointed Bill Wagner as chief executive officer. Matthijs van Leeuwen became chief strategy officer, and then left the company and board of directors in 2018. In January 2022 Bright was acquired by Nvidia. Nvidia cited using Bright's Amsterdam facility as a development center. The acquisition occurred after several layoffs under Bill Wagner. == Customers == Early customers included Boeing, Sandia National Laboratories, Virginia Tech, Hewlett Packard, NSA, and Drexel University. Many early customers were introduced through resellers, including SICORP, Cray, Dell, and Advanced HPC. As of 2019, the company had more than 700 customers, including more than fifty Fortune 500 Companies. == Products and services == Bright Cluster Manager for HPC lets customers deploy and manage complete clusters. It provides management for the hardware, the operating system, the HPC software, and users. In 2014, the company announced Bright OpenStack, software to deploy, provision, and manage OpenStack-based private cloud infrastructures. In 2016, Bright started bundling several machine learning frameworks and associated tools and libraries with the product, to make it very easy to get machine learning workload up and running on a Bright cluster. In December 2018, version 8.2 was released, which introduced support for the ARM64 architecture, edge capabilities to build clusters spread out over many different geographical locations, improved workload accounting & reporting features, as well as many improvements to Bright's integration with Kubernetes. Bright Cluster Manager software was frequently sold through original equipment manufacturer (OEM) resellers, including Dell and HPE. In version 10, Bright Cluster Manager was merged into the NVIDIA Base Command Manager. Bright Computing was covered by Software Magazine and Yahoo! Finance, among other publications. == Awards == In 2016, Bright Computing was awarded a €1.5M Horizon 2020 SME Instrument grant from the European Commission. Bright Computing was one of only 33 grant recipients from 960 submitted proposals. In its category only 5 out of 260 grants were awarded. 2015 HPCwire Editor’s Choice Award for “Best HPC Cluster Solution or Technology" Main Software 50 “Highest Growth” award winner, 2013 Deloitte Technology Fast50 “Rising Star 2013” award winner Bio-IT World Conference & Expo ‘13, Boston, MA, winner of “IT Hardware & Infrastructure” category of the “Best of Show Award” program Red Herring Top 100 Global Award, 2013

Tensor sketch

In statistics, machine learning and algorithms, a tensor sketch is a type of dimensionality reduction that is particularly efficient when applied to vectors that have tensor structure. Such a sketch can be used to speed up explicit kernel methods, bilinear pooling in neural networks and is a cornerstone in many numerical linear algebra algorithms. == Mathematical definition == Mathematically, a dimensionality reduction or sketching matrix is a matrix M ∈ R k × d {\displaystyle M\in \mathbb {R} ^{k\times d}} , where k < d {\displaystyle k